Some good options from the UK to Panama are fairly rare. At this moment german flag carrier Lufthansa is running some interesting promotion on route London – Panama City. Return flights are available already for £303! All charges and checked luggage are included in base fare. If you need some cheap solution to Central America with classic airlines and good routing..
Promotional sale with Lufthansa allows to book these flights in travel dates between 1st of May and 30th of June then 1st of Deptember till 16th of November 2017. Max stay 3 months. Book by 31st of March or until sold out.
UK – Panama for £346 (directly with Lufthansa)
Travel dates to Panama.: Check directly with the airlines as they offer week´s view. Various booking agents are currently offering promotional codes to further discount your accommodation. Consider to use service of Hotelopia, Hotels.com or Venere.
Booking sample of cheap return flights from the UK to Panama from £303 here. In this case you would fly from Birmingham to Panama City on 13th of May. Your return flight from Central America back to Europe would be two weeks later, on 27th of May 2017.